Laatst bewerkt: 19 januari 2017

Internship: Non-mydriatic hand-held retinal imaging

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What will you be doing?

In a lot of applications you can find optical research of TNO, for example: in monitoring the size of the hole in the ozone layer, optimizing oil production, mobile phone chips and in non-invasive glucose measurements for diabetics. The Optics Research Group (70FTE) is one of the leading Optics groups within Europe for design and development of high-performance optical solutions.
TNO Optics works closely together with other research groups within the Nanotechnology Cluster in Delft (200FTE), in particular, with Opto-Mechatronics, Space Systems Engineering and Nano-Instrumentation. Combining our knowledge of optics with expertise available in these research groups enables us to offer complete measurement solutions to our customers. This is strengthened by extensive in-house laboratory facilities and specialized manufacturing capabilities.
We are now looking for an intern for:
Non-mydriatic hand-held retinal imaging
It is the task of primary care professionals to refer ill patients to the right specialist when needed. The general practitioner (GP) acts as a  gatekeeper for secondary care. A more precise referral of patients to secondary care specialists will improve the quality of care and reduce the integral costs of care. This can be achieved by improving the number of diagnostic tools at hand in primary care. However, often the diagnostic tools used by specialists are far too costly and difficult to operate for primary care use. Particularly within the field of diagnosing eye-related diseases there is a need for easy to use, low-cost point of care retinal imaging devices.
Systems at hand are often bulky, expensive and/or need specialized users and need mydriatics to dilate the pupil, the latter being cumbersome to both the GP and the patient. Non-mydriatic retinal imaging methods, i.e. imaging of the retina without the use of mydriatics, are clearly favorable for primary care applications.
Our goal is to create a point of care fundus camera capable of imaging the human fundus and documenting retinal pathology. The final product should combine a high quality full-color image with sufficient resolution and field-of-view at affordable costs in a small (portable) footprint. It should also to be easy to operate by a first line care professional (GP, GP assistant, nursing home physician, etc.) and limit the burden of a measurement to the patient (non-mydriatic).

We have recently developed a small footprint, low-cost, hand-held fundus camera. This device showed rather good image quality, however, mydriatics are needed and the system is not further developed into a product (yet).

As an intern you will modify this device such that it can be used without mydriatics.

The tasks at hand are:

  • Understanding basic principles of fundus camera’s
  • Understanding design of current hand-held fundus camera
  • Modification of design for non-mydriatic use and breadboard application
  • Ordering components
  • Assembly of breadboard setup
  • Lab validation using model eyes
  • Evaluation on healthy volunteers

The project will result in:

  • A breadboard optical setup of the non-mydriatic fundus camera
  • Experimental evaluation of the breadboard model on 10 healthy individuals.

What do we require of you?

We require you to be a Master student in physics with a specific interest in biomedical applications and an expertise in Optics. If you recognize yourself in this profile and are enthusiastic about the assignment, feel free to apply for the position of intern at the Optics department.

What can you expect of your work situation?

TNO is an independent research organisation whose expertise and research make an important contribution to the competitiveness of companies and organisations, to the economy and to the quality of society as a whole. Innovation with purpose is what TNO stands for. With 3000 people we develop knowledge not for its own sake but for practical application. To create new products that make life more pleasant and valuable and help companies innovate. To find creative answers to the questions posed by society. We work for a variety of customers: governments, the SME sector, large companies, service providers and non-governmental organisations. Working together on new knowledge, better products and clear recommendations for policy and processes. In everything we do, impact is the key. Our product and process innovations and recommendations are only worth something if our customers can use them to boost their competitiveness.

What can TNO offer you?

You want to work on the precursor of your career; a work placement gives you an opportunity to take a good look at your prospective future employer. TNO goes a step further. It’s not just looking that interests us; you and your knowledge are essential to our innovation. That’s why we attach a great deal of value to your personal and professional development. You will, of course, be properly supervised during your work placement and be given the scope for you to get the best out of yourself. Naturally, we provide suitable work placement compensation.

Has this vacancy aroused your interest?

Then please feel free to apply on this vacancy! For further questions don’t hesitate to contact us.

Contactpersoon: Arjen Amelink
Phone number: +31 (0)88-86 61186